• The RIDD trial team based at Oxford
  • Clinical examination of Dupuytren's contracture
  • Completing questionnaires on hand function and health
  • Measuring how well fingers can straighten and bend
  • Measuring skin hardness over a Dupuytren's nodule
  • Ultrasound imaging of a Dupuytren's nodule and cord
  • Measuring hand grip strength
  • Separating the Dupuytren's nodule and cord which have been removed from a patient during usual surgery
  • Removed Dupuytren's nodule tissue is analysed in our lab in Oxford

Welcome to the website for the RIDD trial - Repurposing Anti-TNF for treating Dupuytren's disease. The RIDD trial aims to find out whether injections of anti-TNF can help treat early stage Dupuytren's disease. Dupuytren's disease is a common condition which causes the fingers to gradually curl into the palm so they can no longer be straightened. There is currently no approved treatment for early stage Dupuytren's and patients must wait until their fingers have become contracted before being offered surgery. If anti-TNF injections stop, or slow down, the development of Dupuytren's disease it would help maintain hand function and avoid the need for surgery. ______________________________________________________________________________________________________________________________________________ This trial has support from the Department of Health and Wellcome Trust through the Health Innovation Challenge (HIC) Fund. This is a parallel funding partnership to stimulate the creation of innovative healthcare products, technologies and interventions and to facilitate their development for the benefit of patients in the NHS and beyond. For more information please click on the logos at the bottom of the page.

Repurposing Anti-TNF for treating Dupuytren's disease
Recruitment Progress:
Latest participant recruited from: RIDD-2 : Oxford
Date of most recent recruitment: Monday, 8th May 2017